Product Information
Technique
Sample Preparation
Sample Preparation

Samples are often not homogeneous, contain particulates and/or levels of interfering compounds that make analysis difficult, or possibly damage the chromatography system/column. This is often due to the matrix of the sample. The term matrix refers to the surrounding media that contains the analytes and/or contaminants. Some examples of matrices are water (aqueous), urine, soil, plasma or blood. Samples like these are common across a diverse group of industries including: pharmaceutical, clinical, toxicology, environmental testing, agriculture and food and beverage.

Sample preparation is a technique that is used to remove contaminants from a sample and improve chromatographic performance and sample detection. In certain circumstances sample preparation can be used to increase the concentration of analytes.

Sample Preparation
Method Description
Solid Phase Extraction (SPE) Clean-up and concentration of target analytes from blood, urine, plasma, food, and environmental sample matrices
Protein Precipitation (PPT) Rapid removal of proteins from plasma
Phospholipid Removal (PLR) Rapid removal of proteins and phospholipids from biological samples
Filtration Removal of particulates from various samples
QuEChERS An acronym for Quick, Easy, Cheap, Effective, Rugged, and Safe used for multi-residue analysis
Supported Liquid Extraction (SLE) High efficiency solid support used to mimic liquid-liquid extractions
β-Glucuronidase Removal In-well hydrolysis capabilities and rapid removal of β-Glucuronidase from urine samples
Magnetic Beads Used for effective protein and peptide isolation