Product Information
Technique
HILIC HPLC
HILIC provides a unique separation for polar compounds that cannot be effectively separated by reversed phase
HILIC HPLC

HILIC is a particularly useful separation mode for polar organic compounds that are poorly retained by reversed phase. Retention of these polar compounds using reversed phase methods is often difficult because of co-elutions with the solvent front or elutions within the chromatographic region where ion suppression is the greatest.

HILIC HPLC/UHPLC columns draw and retain a water-enriched layer onto the surface of the silica which facilitates the interaction of polar compounds with the stationary phase for increased retention.

HILIC HPLC Phase
Brand Description:
Luna Omega SUGAR Polyamide/amine phase for the separation of polar analytes such as polyols/sugars
Kinetex HILIC Novel core-shell unbonded silica phase provides significant selectivity for retention and separation of polar compounds
Luna HILIC Offers excellent MS sensitivity and selectivity for polar compounds
Luna NH2 Amine phase applicable to multiple modes of chromatography and classes of polar compounds
Luna Silica(2) Ultra-pure, metal-free silica particle that offers great polar selectivity.
bioZen Glycan Higher order separations of released N-Glycans and biomarkers.