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Technique
Chiral HPLC: Phenomenex
Chiral HPLC is used to separate enantiomers.
Chiral HPLC

Chiral chromatography refers to the separation of enantiomers using a chiral HPLC column, an HPLC column that is packed with a chiral stationary phase (CSP). Enantiomers are separated based on the number and type of each interaction that occurs during their exposure to the chiral stationary phase. Some chiral stationary phases (CSPs) are able to separate a wide range of chiral compounds, while others are useful only for specific types of chiral compounds.

Normal phase solvents are commonly used for chiral HPLC separations, however, reversed phase solvents can also be used with certain types of chiral stationary phases. Approximately 60% of all pharmaceutical drugs are chiral. Common chiral stationary phases used for chiral HPLC columns are polysaccharide, ligand exchange, protein, helical polymers, macrocyclic, and Brush (Pirkle-concept).

Brand Description:
Lux Polysaccharide-based chiral HPLC column allows for screening under reversed, polar organic, and normal phase
Chirex Traditional brush (Pirkle-concept) chiral LC columns