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Product Information
Phase Detail
Strata-XL-C SPE Products
Strata-X-L-C solid phase extraction (SPE) sorbent is a polymeric large particle strong cation exchange (SCX) phase SPE sorbent for viscous samples

Strata-XL-C SPE Products

Large Particle Strong Cation Mixed-Mode Solid Phase Extraction (SPE)

A strong cation-exchange functionalized polymeric sorbent that allows for complete retention of basic compounds with a pKa less than 10.5, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.  The large particle format is ideal for processing large volumes or viscous samples.

Brand
Strata-X
Recommended Use
Extraction of weakly basic compounds, present in large volume or viscous samples

3 Mechanism of Retention

Strong Cation-Exchange

π-π Bonding

Hydrophobic Interaction

Available Formats

Strata 96 Well Plate
96-Well Plates
1, 3, and 6mL Tubes
Giga Tubes (12-150mL Tubes)

Starting Method

For Bases with pKa ≤ 10.5

Column:
1 mL Methanol
Equilibrate:
1 mL Acidified Water
Load:
Diluted Acidified Sample
Wash 1:
1 mL 0.1 N HCI in Water (collect this fraction to analyze Polar Neutrals)
Wash 2:
1 mL 0.1 N HCI in Methanol (collect this fraction to analyze Neutrals/Acids)
Elute Any Acids:
2x 500 µL 5 % NH4OH in Methanol

Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.