Product Information
Phase Detail
Strata-XL-A SPE Products
Strata-X-L-A solid phase extraction (SPE) sorbent is a polymeric large particle strong anion exchange (SAX) phase SPE sorbent for viscous samples
Strata-XL-A SPE Products
Large Particle Strong Anion Mixed-Mode Solid Phase Extraction (SPE)

A large particle, strong anion-exchange functionalized polymeric sorbent that allows for complete retention of acidc compounds with a pKa greater than 2, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound. The large particle format makes this sorbent ideal for processing large volumes or viscous samples.

Brand
Strata-X
Recommended Use
Extraction of weakly acidic compounds present in viscous samples
3 Mechanism of Retention

Strong Anion-Exchange


π-π Bonding

Hydrophobic Interaction

Available Formats
Strata 96 Well Plate
96-Well Plates
1, 3, and 6 mL Tubes
Giga™ Tubes (12-150 mL Tubes)
Starting Method

For Acids with pKa > 2

Column:
1 mL Methanol
Equilibrate:
1 mL Water, pH 6-7
Load:
Diluted Sample pH 6-7
Wash 1:
1 mL 25 mM Ammonium Acetate Buffered, pH 6-7
Wash 2:
1 mL Methanol (collect this fraction to analyze Neutral/Bases)
Elute Acids:
2x 500 µL 5 % Formic Acid in Methanol

Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.