Product Information
Phase Detail
Strata-X-AW SPE Products
Strata-X-AW solid phase extraction (SPE) sorbent is a polymeric weak anion exchange sorbent that can be used for the cleanup of strong acids
Strata-X-AW SPE Products
Weak Anion Mixed-Mode Solid Phase Extraction (SPE)

A weak anion-exchange functionalized polymeric sorbent that allows for complete retention of acidic compounds with a pKa less than 5, making 100% organic wash conditions possible. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.

3 Mechanism of Retention

Weak Anion-Exchange



π-π Bonding

Hydrophobic Interaction


Available Formats
96-Well Plates
Microelution 96-Well Plates
1, 3, and 6 mL Tubes
Giga™ Tubes (12-150 mL Tubes)
Starting Method

For Acids with pKa ≤ 5

Column:
1 mL Methanol
Equilibrate:
1 mL Water, pH 6-7
Load:
Diluted Sample pH 6-7
Wash 1:
1 mL 25 mM Ammonium Acetate Buffered, pH 6-7
Wash 2:
1 mL Methanol
Elute Any Acid:
2x 500 µL 5 % NH4OH in Methanol
Elute Weak Acids:
2x 500 µL 5 % Formic Acid in Methanol

Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.