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Product Information
Phase Detail
Strata-X SPE Products
Strata-X solid phase extraction (SPE) polymeric SPE sorbent that offers reversed phase selectivity and gives strong retention of neutral, acidic, or basic compounds

Strata-X SPE Products

Reversed Phase Solid Phase Extraction (SPE)

A reversed phase functionalized polymeric sorbent that gives strong retention of neutral, acidic, or basic compounds under aggressive, high organic wash conditions. This sorbent relies on 3 mechanisms of retention: pi-pi bonding, hydrogen bonding (dipole-dipole interactions), and hydrophobic interaction.

Brand
Strata-X
Recommended Use
Extraction of basic drugs from biological samples

3 Mechanism of Retention



π-π Bonding



Hydrogen Bonding
Dipole-Dipole Interactions



Hydrophobic Interaction

Available Formats

96-Well Plates
Microelution 96-Well Plates
1, 3, and 6 mL Tubes
Giga™ Tubes (12-150 mL Tubes)
On-line Cartridges

Starting Method

For Neutral Compounds

Column:
1 mL Methanol
Equilibrate:
1 mL Water
Load:
Diluted Sample
Wash:
1 mL 5-60 % Methanol
Elute:
2x 500 µL 2 % Formic Acid in Methanol/Acetonitrile

Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.