Product Information
Phase Detail
Kinetex Core-Shell Polar C18
Kinetex Core-Shell Polar C18 HPLC Columns is a L1 column with unique polar retention

Kinetex Core-Shell Polar C18

Increase Polar Selectivity and Performance!

The Kinetex® 2.6 µm Polar C18 is a core-shell based particle with a polar modified surface and a C18 alkyl phase. This versatile column can easily upgrade existing fully porous 5 µm and 3 µm methods to shorten run time, increase sensitivity, and even provide greater resolution with much higher efficiency levels. Combined with being 100 % aqueous stable the Kinetex Polar C18 is a unique column that combines performance and selectivity.

  • Compatible with All Analytical HPLC/UHPLC Systems*
  • L:1 C18 with Unique Polar Retention
  • Compatible with 100 % Aqueous Mobile Phases
  • USP: L1

*Kinetex analytical columns are compatible with all LC system with standard LC column end-fittings threaded in 10-32. Please contact us at Phenomenex.com/chat for any questions and information about fitting compatibility and any other column internal diameters.

Particle Size
2.6, 3
Recommended Use
Combined C18 and polar modified surface that provides polar and non-polar retention alongside 100% aqueous stability

C18 and Polar Selectivity

Combined C18 and polar modified surface that provides polar and non-polar retention alongside 100 % aqueous stability.



hydrogen_bond

Increase Polar Retention and Hydrophobic Selectivity

Increase polar selectivity without sacrificing hydrophobic selectivity with the Kinetex Polar C18. The Kinetex Polar C18 is an excellent all-purpose, 100% aqueous stable phase for use with multi-compound mixes that contain polar and non-polar compounds, or even single class methods that have closely related compounds, impurities, or metabolites.

Aromatic Compound Comparison

Conditions for all columns:

Columns:
Kinetex 2.6 µm Polar C18
AQUA 3 µm C18
Dimension:
150 x 4.6 mm
Mobile Phase:
A: 20 mM Potassium Phosphate (pH 1.5)
B: Methanol
Gradient:
Time (min)
0
1
7
7.01
14
 
% B
5
30
30
0
0
Flow Rate:
1.2 mL/min
Temperature:
22 °C
Injection Volume:
5 µL
Detection:
UV @ 210 nm
Analytes:
1. Thiamine
2. Nicotinamide
3. Pyridoxal
4. Pyridoxine
5. Pantothenic Acid

Kinetex Where Performance Meets the Right Selectivity

Quickly improve the productivity and performance of your existing methods and utilize the core-shell advantage to deliver performance you need at backpressures the system can handle. Select from a variety of column selectivity to find the right phase for the application.

Polar Compound Phase Comparison

Conditions for all columns:

Columns:
Kinetex 2.6 µm C18
Fully Porous 1.9 µm C18
Kinetex 2.6 µm Polar C18
Kinetex 2.6 µm PS C18
Dimension:
100 x 2.1 mm
Mobile Phase:
A: Water with 0.1 % Formic Acid
B: Acetonitrile with 0.1 % Formic Acid
Gradient:
Time (min)
0
4
4.1
7
 
% B
3
100
3
3
Flow Rate:
0.5 mL/min
Temperature:
25 °C
Detection:
MS/MS SCIEX® API 4000™
Sample:
Acesulfame

Column Back-Pressure (bar) RT (min) Peak Height (cps) Est. T0* (min)
Kinetex 2.6 µm C18 252 0.67 1.8E+06 0.34
Fully Porous 1.9 µm C18 432 1.07 1.0E+06 0.46
Kinetex 2.6 µm Polar C18 237 1.45 2.1E+06 0.34
Kinetex 2.6 µm PS C18 241 1.85 2.2E+06 0.34