Product Information
Phase Detail
Kinetex Core-Shell HILIC HPLC Columns
Kinetex Core-Shell HILIC HPLC columns provide separation and retention for polar compounds under HILIC conditions
Kinetex Core-Shell HILIC HPLC Columns
Hydrophilic Polar Selectivity and Performance!

The Kinetex HILIC is a core shell based particle with a unbonded silica phase is used under hydrophilic interaction chromatography conditions to provide the selectivity needed for the retention and separation of polar compounds. This versatile column can easily upgrade existing fully porous 5 µm and 3 µm methods to shorten run time, increase sensitivity, and even provide greater resolution with much higher efficiency levels.

  • Compatible with All Analytical HPLC/UHPLC Systems*
  • Unique Polar Retentive L3 Silica
  • Unbonded Silica Phase

*Kinetex analytical columns are compatible with all LC system with standard LC column end-fittings threaded in 10-32. Please contact us at for any questions and information about fitting compatibility and any other column internal diameters.

Carbon Load
Surface Area (m²/g)
Particle Size
Recommended Use
Retention and separation of polar compounds hydrophilic interaction chromatography conditions
Alternative Polar Selectivity to a C18  
A Core-Shell based silica phase that combines high-performance with novel polar HILIC selectivity.
Increase Polar Retention
Used under HILIC running conditions, this phase provides the highest polar selectivity for retention and separation of hydrophilic compounds.

Kinetex HILIC
50 x 2.1 mm
Part No.:
00B 4461 AN
Mobile Phase:
A: Acetonitrile
B: 100 mM Ammonium Formate pH 3.2
Flow Rate:
0.4 mL/min
30 ˚C
UV @ 210 nm
1. Norepinephrine
2. Epinephrine