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Aggregate Analysis of Monoclonal Antibodies using bioZen SEC-3 Column
Monoclonal antibody (mAb) aggregates have significant implications in safety, immunogenicity, and efficacy for therapeutic drug development. Size exclusion chromatography (SEC) is one of the laboratory methods used to determine the extent of aggregation of a protein. This method demonstrates the separation of three mAbs trastuzumab, infliximab, and cetuximab with the use of the bioZen SEC-3 column.
Aggregate Analysis of Monoclonal Antibodies using bioZen SEC-3 Column
Monoclonal antibody (mAb) aggregates have significant implications in safety, immunogenicity, and efficacy for therapeutic drug development. Size exclusion chromatography (SEC) is one of the laboratory methods used to determine the extent of aggregation of a protein. This method demonstrates the separation of three mAbs trastuzumab, infliximab, and cetuximab with the use of the bioZen SEC-3 column.
Document Type:
Technical Notes
Techniques:
Brands:
Separation Modes:
Size Exclusion
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