Proton Pump Inhibitors Including Rabeprazole and Pantoprazole by Chiral HPLC (TN-1102)

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Proton Pump Inhibitors Including Rabeprazole and Pantoprazole by Chiral HPLC (TN-1102)

This technical note demonstrates the successful separation of protein pump inhibitors (PPI) Omeprazole, Lansoprazole, Rabeprazole, and Pantoprazole using Lux polysaccharide-based columns. These chiral separations indicate the potential to prepare enantiomerically pure forms of racemic active ingredients Pantoprazole (Protonix) and Rabeprazole (AcipHex) using chiral chromatography.

Document Type:

Technical Notes

Target Industries:

Biopharmaceutical Analysis, Pharmaceutical

Techniques:

HPLC, HPLC-Chiral

Brands:

Separation Modes:

Chiral

Phases:

Lux Cellulose-1, Lux Cellulose-2, Lux Cellulose-3 , Lux Cellulose-4

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